Buffalo-Washington matchup will have a decidedly Carolina feel. Chicago's future at quarterback has arrived, as the former Ohio State star returns to the Buckeye State. He is the Bears' 36th different starting quarterback since -- the second most in the NFL over that span behind the Browns Bold prediction: Fields will rush for two touchdowns. He is still a work-in-progress in the passing game, but there is no denying his ability to run with the football.
Don't be surprised if Fields also finishes with close to rushing yards in his NFL regular-season starting debut. The best completion percentage by a Browns quarterback through the team's first three games is Injuries: Bears Browns. What to know for fantasy: Chicago running back David Montgomery has posted more than And they have covered each of their past three games against Cleveland.
Matchup must-reads: Fields to get first start OBJ closer to return but taking it 'day by day' Now that Fields is starting, there's no turning back Landry to IR, out at least three days. What to watch for: Can the Lions fix their mistakes and put together a complete game?
Against San Francisco in Week 1, they started poor before ending strong. Then against Green Bay in Week 2, they got off to a hot start and folded late. The Lions are looking to avoid an start for first time since , while this Baltimore team enters Ford Field with 41 straight games with rushing yards -- the second-longest streak in NFL history. Bold prediction: The Ravens' defense will not allow a touchdown after giving up the second-most points in the NFL over the first two weeks.
After not blitzing against Kansas City, Baltimore will get back to its aggressive style of defense in Detroit. In their only meeting against Lions QB Jared Goff , the Ravens intercepted him twice and forced him to throw off-target on Stat to know: Jackson has four straight games with 80 rushing yards -- the longest streak of his career. Injuries: Ravens Lions. What to know for fantasy: Lions tight end T.
Hockenson had never had a game with at least eight catches and a touchdown in his NFL career entering this season. However, he is the only player in the NFL who has produced that stat line in both Weeks 1 and 2 this year.
Betting nugget: Goff is ATS in his career as a double-digit road underdog, and Baltimore has covered each of its past three games against Detroit. Matchup must-reads: Letdown after emotional win? Ravens' Jackson ranks among best at avoiding upsets Lions are looking to trade LB Collins Jackson misses practice Thursday with illness, but source says he's OK for Sunday.
What to watch for: Steelers edge rusher T. Roethlisberger, who is against the Bengals, might be able to play through the pain of the left pec injury , but if the Steelers' embattled offensive line can't withstand a pass rush led by Bengals defensive end Trey Hendrickson , it could be another long day for the QB. Defensively, the Steelers have a rash of injuries that could make it difficult to defend the deep ball from Bengals signal-caller Joe Burrow -- something Pittsburgh didn't do well in the loss against the Raiders.
Bold prediction: Steelers running back Najee Harris will get scrimmage yards. The Steelers have had fewer than rushing yards in eight straight games, the longest active streak in NFL. But they should be able to get favorable matchups for Harris in the middle of the field against Cincinnati. Stat to know: Pittsburgh receiver JuJu Smith-Schuster has gone 23 straight games without reaching receiving yards, the longest streak of his career.
On the other sideline, Bengals receiver Ja'Marr Chase has the chance to become the second player in NFL history with a touchdown catch of at least 40 yards in each of his first three career games Billy Howton in Injuries: Bengals Steelers.
What to know for fantasy: Cincinnati running back Joe Mixon has touched the ball 51 times in his past three games against the Steelers and hasn't scored once. Betting nugget: The Steelers have covered six of their past eight home games against the Bengals.
Matchup must-reads: Bengals loss to Bears raises questions about Taylor Roethlisberger to do 'everything he can' to play vs. What to watch for: The Titans' banged-up offensive line is facing a Colts run defense that is allowing an uncharacteristic yards per game on the ground. Over the past three seasons, the Colts' run defense allowed or more rushing yards only three times. Regardless of who is blocking, expect the Titans to give running back Derrick Henry the ball early and often.
Henry picked up or more yards in each of his past three games facing the Colts. Bold prediction: Titans receivers A. Brown and Julio Jones will each have yards, and Henry will have at least yards on the ground. The Colts' defense, as linebacker Darius Leonard said, has struggled putting together four quarters of consistent play for a season and a half. Leonard and Co. Injuries: Colts Titans. What to know for fantasy: The Colts saw a receiver score over 17 fantasy points in both meetings with the Titans last season.
Matchup must-reads: At , Colts need Wentz to protect himself from himself Tannehill and Jones' chemistry heats up in Week 2 for Titans With Wentz injured, fair to question Colts' QB depth Titans RB Henry looks to keep yard streak alive against Colts.
What to watch for: This is not a good matchup for the Jaguars. They've given up yards and four passing touchdowns, and they haven't created a turnover in their two losses.
The quarterbacks they have faced? Tyrod Taylor and Teddy Bridgewater. Solid players but not upper echelon QBs. Now comes Arizona's Kyler Murray , who has thrown for yards and seven touchdowns with three interceptions in victories over Tennessee and Minnesota. Bold prediction: Murray will throw for yards and three touchdowns while running for another yards and a touchdown. He is seeking to become the first Cardinals player with back-to-back yard passing games and can tie Carson Palmer three for the most yard passing games in franchise history.
Stat to know: The Jaguars have lost 17 straight games. With a loss, they would tie the Houston Oilers for the fifth-longest losing streak in NFL history. Injuries: Cardinals Jaguars. What to know for fantasy: Receiver Marvin Jones Jr. Betting nugget: Arizona has covered each of its past three games against Jacksonville, and the Jags have failed to cover each of their past three games as a home underdog.
Meyer 'concerned' that kicker Lambo is no longer Lambomatic for Jaguars What to watch for: It's a battle of teams, and it's getting late early for these two teams. Who at least wants to pretend they are going to be a playoff contender this season?
Neither team can afford to lose this one. Atlanta is seeking to avoid eight straight losses for the first time since , while New York is attempting to prevent consecutive starts for the second time in franchise history It's one of those games. Bold prediction: Giants running back Saquon Barkley will return to form with yards rushing and a couple of touchdowns. The Falcons have the sixth-worst run defense in the league 4. For a while, Barkley was considered that. Since then, they are just ATS in such spots.
Matchup must-reads: Mahomes won't point to Chiefs' defense to explain his turnover troubles Rivera frustrated as missed opportunities mount MCL sprain to sideline Edwards-Helaire 'a few weeks' Chiefs address weekly burden of being in the 'crosshairs'.
ET Fox Matchup rating: What to watch for: Keep an eye on Carolina's offensive line. It has given up eight sacks and 19 quarterback hits the past two weeks, a big reason for a two-game losing streak.
The Panthers likely will have back the left side of their line tackle Cameron Erving and guard Pat Elflein , but even with them, teams were getting pressure on Sam Darnold. Bold prediction: Darnold will notch his seventh career game with three interceptions, which will be the most by any quarterback since he entered the NFL in The Vikings' pass rush ranks second with 3.
What Minnesota does up front will yield a big day on the back end of the defense in the form of multiple interceptions by the secondary. Stat to know: The Panthers' defense is allowing 4. Injuries: Vikings Panthers. What to know for fantasy: Minnesota quarterback Kirk Cousins is averaging Minnesota is ATS in its past five in that spot.
Matchup must-reads: Unimpressive win over Lions highlights flaws with Vikings' conservative approach Can Panthers' Darnold, Anderson re-create chemistry found with Jets Darnold knows he has to perform better under pressure. What to watch for: The Rams have allowed a league-low four sacks through five games, and only one team has produced fewer than the Giants' eight sacks.
If not, it's going to be another long day for the Giants' defense and a good afternoon for Stafford and Los Angeles. Bold prediction: Stafford will pass for four touchdowns in a blowout win. The Giants' defense is allowing Stafford's connection has been just a bit off with receivers the past two games, so look for coach Sean McVay to dial up the passing game to get him in rhythm with his playmakers early.
Injuries: Rams Giants. What to know for fantasy: Los Angeles running back Darrell Henderson has accounted for That's a higher rate than Dalvin Cook and Austin Ekeler hold this season with their respective teams.
Jones 'on track' to return from concussion protocol, face Rams Stafford says thumb is fine, Woods gets going in Rams' offense Toney is the new 'Human Joystick' and a fun addition to Giants offense. A victory over hated Green Bay would do wonders for Chicago's confidence. The Packers, meanwhile, are just hoping for business as usual. Green Bay quarterback Aaron Rodgers lifetime versus Chicago has trounced the Bears throughout his illustrious career.
Bold prediction: Rodgers' turnover-free streak during the Packers' current four-game winning streak against the Bears will come to an end -- and it will cost them the game. Rodgers has 10 touchdown passes without a turnover in the past four meetings with Chicago, but the Bears' defense looks strong this season and could be the difference in pulling off an upset.
Stat to know: Justin Fields will be the 20th different starting quarterback that the Bears have used against the Packers since The Packers have used only three different starting QBs vs. Injuries: Packers Bears. What to know for fantasy: Pass-happy game script? Packers receiver Davante Adams has scored or gone over receiving yards in seven of his past eight games against the Bears, while running back Aaron Jones averages under 4.
Betting nugget: The Packers have won nine of the past 10 meetings in this rivalry, covering the spread in seven of those instances. Matchup must-reads: Rodgers runs out of time when trying to recall all of the Bears' QBs since Bears' Fields says he'll be OK to play vs.
How LB Campbell went from out of work to star of Packers' defense Bears showing offensive identity under new playcaller Lazor. What to watch for: Will the Colts' pass rush have a big game against Houston's depleted offensive line? The Texans will be without their best offensive lineman, left tackle Laremy Tunsil finger , against the Colts. That means an Indianapolis front led by DeForest Buckner will have an opportunity to put pressure on Houston rookie quarterback Davis Mills, who has been sacked 11 times in four games.
And there's a chance the Colts could have rookie pass-rusher Kwity Paye hamstring back after he missed the past two games. Bold prediction: If Colts receiver T. Hilton returns from injury neck and plays on Sunday, he'll continue his success against the Texans with a big game, reaching receiving yards.
In 18 career games against Houston, Hilton has 97 catches for 1, yards and 11 touchdowns. Stat to know: After throwing for yards last week, Mills can become the first Texans rookie with plus passing yards in consecutive weeks.
Injuries: Texans Colts. What to know for fantasy: In each of the past five seasons, Hilton has had a game with over 19 fantasy points against Houston as Indianapolis' WR1. Michael Pittman Jr. Matchup must-reads: Culley on start: 'We've been the enemy' Wentz wants Colts to learn from Monday's loss and develop 'killer instinct' Colts blow point lead, continue downward spiral. What to watch for: Although the Lions are one of two winless teams, this group could easily have two wins this year if it weren't for gut-wrenching losses to Baltimore and Minnesota on game-deciding field goals.
So can they avoid starting for the first time since , when the squad infamously finished ? First-year Lions coach Dan Campbell actually experienced that as a player. And look, nothing I'm going to tell them is going to make them feel any better," Campbell said to any disappointed fans. Look, everybody is frustrated. Bold prediction: Bengals wide receiver Ja'Marr Chase will have a yard completion and receiving yards.
The Lions give up more yards per completion than any other team. And so far, Chase has been the team's big-play receiver. Stat to know: Joe Burrow is the first QB in Bengals history with multiple touchdown passes in each of the team's first five games. He seeks to join Dan Marino as the only first- or second-year quarterbacks with multiple passing touchdowns in their teams' first six games. Injuries: Bengals Lions. What to know for fantasy: Chase is the second rookie WR with receiving yards and five receiving TDs through five games.
The other? Jimmy Clausen's going to be throwing quite a bit in the second half. By keeping their opponent out of the end zone, the Bears don't have to score that much to win. Dazzy Jay Cutler will appreciate that. This will be Sunday's best game. The Giants defense is capable of preventing Arian Foster from yards, and they will force Matt Schaub to throw more often than any week yet this year. The Giants great pass rush will get their share of sacks and hurries.
Across the sideline, however, the Texans front four are also very good. They will put similar pressure on Eli Manning. Although the Jaguars aren't exactly a high-powered offense, they will be able to put points on the board against Buffalo. After a great effort in Week 1 against Miami, the Bills have yielded plus points each week. And because the Bills just can't seem to make plays in the passing game, this is going to be a blowout.
The last of the unbeatens fall this week. The Chiefs just don't have enough firepower on offense to match score-for-score with the Colts. After three road games in four weeks, Indianapolis is happy to be home, where they do much better, especially on offense: They clobbered the Giants, , their only other time at Lucas Oil Stadium in Kansas City will hang in the game early on thanks to their special teams, but Matt Cassel's inconsistencies will show up against the Colts fast defense.
No other team in the NFL is better equipped to match up with the Broncos passing offense than the Ravens. The pass rush will get to Kyle Orton several times, and with their secondary and linebackers, Baltimore will force turnovers. Denver's only shot at winning this one on the road is to go all out.
They're going to do it in the second half anyway, so just abandon the run from the get-go. That way, maybe one of Denver's refurbished wide receivers can score a touchdown or two to grab an early lead.
Champ Bailey and the Broncos secondary are capable of limiting what Baltimore does downfield; it's up to their front seven to hem in the short stuff. After four weeks of being uncharacteristically subdued, the Saints offense gets back on track this week.
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